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In response to what FDA Commissioner Gottlieb termed an e-cigarette use epidemic among youth, driven in part by the youth-appealing flavors of e-cigarettes, in November 2018, the FDA announced restrictions on the sale of flavored e-cigarettes

But frequent marijuana use causes inappropriate activation of CB1, which can cause inflammation and atherosclerosis, and it is associated with obesity, cancer and diabetes

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They have proposed developing a vape retailer and distributor licensing scheme to make it harder for the rogue traders to get away with underage and illicit sales

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