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Upon stimulation by reactive oxygen species (ROS), extracellular ATP, or lysosomal destabilization, NLRP3 activation drives the maturation and release of pro-inflammatory cytokines such as IL-1 and IL-18, which in turn promote neutrophil recruitment and tissue injury

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Lung conditions, such as pneumonia or popcorn lung, are also potential consequences of vaping

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So, whenever I felt sad, or stressed, or particularly carefree (like that night in the back of the rideshare), the emotional pangs returned, and I often relapsed