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Since the ATGLi blocks lipolysis in other tissues, including the liver, we conducted the G49 treatment in mice with Atgl deletion exclusively in adipocytes (ATGL a dipoCre ) to elucidate the effect of G49 in WAT lipolysis-mediated beiging signature in eWAT and to decipher whether WAT lipolysis accounts for BAT activation and weight loss upon G49 treatment

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