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DAVID analysis of downregulated proteins yielded six significant clusters, which included extracellular matrix, cell adhesion/migration, fibronectin, endoplasmic reticulum, actin cytoskeletal signaling, and actin filament binding, implicating the cytoskeleton as a major target (Fig

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Nicotine is in tobacco products like cigarettes, e-cigarettes and other vaping products like JUUL, smokeless tobacco and all other forms of tobacco including hookah and cigars