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Conversely, there has been little decline in smoking in most low- and middle-income countries (LMICs) with over half of all men continuing to smoke in large populations in Asia (China, Indonesia), as well as the Pacific Islands

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This increases susceptibility to infections worsens progression of lung disease. The researchers now plan to investigate exactly which MAIT cell pathways are impacted by cigarette smoke in order to learn how to better treat COPD and other lung diseases.