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It generally continues unchanged during the switch because it works through an entirely different mechanism (reducing hepatic glucose production) and does not interact with incretin receptors

After your last dose, it takes about 5 weeks (5 half-lives) for 97% of the medication to be eliminated from your system

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This is why its important to store peptides in sealed containers away from direct light to help preserve the integrity of your samples (Sigma-Aldrich, 2023b)

The molecular mechanisms governing hepatic lipid homeostasis and the counter regulatory mechanisms related to a chronic lipid overload and NAFLD are both complex and tightly interconnected