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Cigarette smoke, carbon monoxide and nicotine induce some of the biochemical, anatomical and pathophysiological changes seen in CHD, but prospective epidemiological studies document that cessation of cigarette smoking results in reduced mortality from CHD. Editorial The Grave Facts About Smoking, Medical Journal of Australia, July 26, 1975, Pages 120-121 What Did We Do About It

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For example, multiple types of tobacco can be grown just from Nicotiana tabacum when one brings seeds to grow in a different place, with different factors soils, weather, or harvest period

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