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While less common than dryness or fatigue, some individuals may experience bloating or other gastrointestinal disturbances

Beyond the gut, the microbiota influences distant organs through the production of bioactive compounds that enter the bloodstream, affecting metabolic functions, immune responses, and even neurobehavioral processes (Roman-Prez et al., 2021)

In the two lymphoid cell lines, it was shown that all studied polyphenols when used in combination with each topoisomerase II inhibitor caused a synergistic or additive decrease in cell proliferation, G 2 M or S phase cell-cycle arrest and apoptosis

5c, see arrowhead), showing that these two antigens exhibit almost mutually exclusive staining patterns among patients and within the tumor from the same patient

They demonstrate what becomes possible when we treat the whole person rather than isolated symptoms