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The study results suggested that polyphenol consumption escalated with age, with a more pronounced increase observed in male subjects

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However, they emphasize that these drugs have additional health benefits that are often overlooked, particularly in the context of thyroid health

FOXO6, as the most evolutionarily divergent member of this group, exhibits tissue-specific expression, particularly in liver, muscle, and neural tissues, and its effects on insulin signaling significantly differ from the other isoforms

FIGURE 8 Statements Author contributions YZ, SdB-S, MdB, and SH conducted the experiments and performed the statistical analysis