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From a fiscal perspective, illicit tobacco trade only benefits a few (often criminal enterprises) at the cost of forgone tax revenues for the government, which results from taxes not being paid on tobacco products

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CYP1A1 is also involved in detoxifying dioxin , which is a persistent organic pollutant that is carcinogenic.[ref] A study on workers in China showed that those with CYP1A1 variants had lower acetylcholinesterase levels due to glyphosate (RoundUp ingredient) exposure