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2.10 Functional annotation of differentially expressed genes The DEGs were subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis

This section relies heavily upon prior systematic reviews 17 , 31 , 102 109 and several highly relevant and informative individual studies

Conversely, a recent systematic review by Almeda and Gmez-Gmez (28) revealed a decline in cigarette smoking during the SARS-CoV-2 pandemic in the majority of the included cohort studies which might be related to the reduction in social gatherings among other things

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