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It was followed by tobacco (45), nonprescription opioids (33), cocaine (19), methamphetamine (19), and cannabis (15). The analysis, which was supported with Canadian Institutes for Health Research grant funds, concluded that marijuanas biggest harm comes not from its effect on consumers but instead is related to the illegal market

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In line with these previous studies, our own research demonstrated that both current and former smoking were associated with an increased risk of trouble sleeping and depression, with the risk becoming more pronounced with higher smoking intensity