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The toxic components of cigarette smoke, including nicotine, tar, and various carcinogens, can impair the functioning of the testes, which are responsible for synthesizing testosterone

Though the study found that smokers were more likely than non-smokers to have lung cancer, and that the prevalence of the disease rose with the quantity smoked, the design of the study still left room for Fishers dreaded confounding problem

Over Half of Psychology Studies Fail Reproducibility Test. Nature News, August 27, 2015

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See McCreight, "Firewater and Forked Tongues: A Sioux Chief Interprets U.S