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It may also affect intellectual development

The study has several limitations, they noted, including that most participants in the cohort studies were white and that the associations between smoking and mortality could be confounded by differences between smokers and nonsmokers with respect to risk factors including diet, physical activity, and access to medical care. The studys findings underscore the need for continued efforts to reduce the number of people who smoke, wrote Graham Colditz, M.D., of the Washington University School of Medicine, in an accompanying editorial

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MMWR Morb Mortal Wkly Rep 2019;68:919927

Dark clouds hung over smoking as a likely risky activity long before the watershed case control studies on smoking and lung cancer were published in 1950 by Doll and Hill (on British smokers) and Wynder and Graham (on American smokers)