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If your hives havent gone away after a few days or theyre not responding to at-home or over-the-counter treatments, make an appointment to see a primary care doctor

For example, carriers of the HLA-DRB1 * 01:03 allele (approximately 3% of patients) have a greater than 40% risk of requiring major intestinal surgery within 3 years of diagnosis (Vestergaard et al., 2024)

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In very advanced stages those changes may become painful

& Topkaya, S