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These changes coincided with decreased antioxidant pathways (system xc-, glutathione peroxidase 4, and glutathione) and increased lipid peroxidation

This dynamic response suggests that upon TCR activation, T cells undergo rapid rewiring of their sterol metabolism, which is characterized by increased sterol synthesis and uptake to support membrane synthesis during T cell expansion

78 IVD cells of elderly subjects with disc degeneration had reduced SPARC expression

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About this article Cite this article Reed, M.C., Thomas, R.L., Pavisic, J