It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Green et al., 2017)
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The overall impression remains within normal parameters
A 2026 UK review of the neuroinflammation / white-matter / small-fibre mechanism, the 2025 BSR guideline, the BDNF / HGF/c-Met case, the elevated lymphoma risk vs pro-proliferative c-Met and why specialist care, not a peptide, comes first Read the full review Microbiome & Gut-Brain Neuroscience 16 June 2026 Dihexa for Gut-Brain Axis Brain Fog: IBS, SIBO, Leaky Gut, the Microbiome & the 2026 UK Review My guts a mess and so is my head are they connected? Increasingly, the science says they can be