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Also observed a significant increase in cytochrome P450 (CYP)-CYP1A1/2, CYP2B1/2 and CYP3A to an enhanced cancer risk from the widely bioactivated e-cig vapour procarcinogens associated with an increased risk of lung cancer with CYP induction and/or CYP polymorphisms (Table 3)

For 8th graders, it was roughly 11%

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Exposure to the e-cigarette flavoring chemicals and e-liquids led to higher production of two well-established biomarkers for inflammation and tissue damage mediated by oxidative stress