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It is the why NNMT is interesting at all paper

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Cellular atypia is present

2 The biosynthetic pathway of glucoraphanin: from gene to metabolite The chemopreventive promise of SFN is fundamentally rooted in the metabolic capacity of its plant source

With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death