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Similar content being viewed by others Introduction Emerging evidence indicates that gut microbiota-host interactions play a key role in the pathophysiology of type 2 diabetes and modulates energy homeostasis, glucose homeostasis and insulin resistance 1,2,3,4,5,6,7,8,9

-endorphin, the POMC-derived opioid peptide, has the capacity to upregulate melanogenesis and melanin distribution by promoting maturation of melanocytes and arborisation of their dendritic processes, thus increasing the efficacy of the transfer and distribution of melanosomes to neighbouring keratinocytes [23, 29]

But they cannot address the movement dysfunction, muscle weakness, compensatory patterns, and proprioceptive deficits that develop alongside shoulder injuries