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Factors with an overall unclear association according to the systematic literature review were not ranked but were given a low positive or negative weighting based on strength of evidence (taking into consideration the number of studies demonstrating consistent associations, geographic spread, and individual study characteristics)

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Alcohol Compared to other substances of abuse, alcohol is the most commonly misused substance leading to addiction among people who have served

By the 17th century, tobacco had reached the shores of Africa, Asia, and the Middle East, carried by traders and colonizers

Hokanson, MPH, PhD