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According to the sequence and structural alignment of these identified phosphatases, an apyrase encoded by the ENTPD2 gene, that is expressed in different tissues, including colon and small intestine, may possess the ThDP phosphatase activity in mammals (140)

Treatment of hypertension during pregnancy as a replacement for ACE inhibitors & ARBs The patient can be switched back to an ACE inhibitor or ARB once pregnancy is over Notes: Methyldopa is the L-isomer of alpha-methyldopa References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

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"In recent weeks, Novo Nordisks commercial team increasingly pressured us to control clinical standards and steer patients to Wegovy regardless of whether it was clinically best for patients