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GLP-1 receptors and pain pathways GLP-1 receptors are widely expressed throughout both the central and peripheral nervous systems

Oral semaglutide is a prescription GLP-1 medication taken as a daily tablet that may support weight loss by helping the body better regulate appetite and food intake

Most patients experience peak side effects during the first 24 weeks of treatment or after dose increases

Split dosing protocols explained If you and your healthcare provider decide to explore split dosing, here is what the various protocols look like in practice

The most common side effects are gastrointestinal: nausea, stomach discomfort, bloating, or changes in bowel habits