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doi:10.1111/j.1365-2133.1967.tb11465.x

However, the quality of evidence was very low and therefore it remains uncertain whether physical activity is helpful in men experiencing urinary symptoms caused by benign prostatic hyperplasia

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It may be that the main impact of physiologic insulin regimens and insulin glargine, in particular, is that the separation of prandial and basal components improves our understanding of insulin use, simplifies dosing adjustments, and allows patients more flexibility in meal timing