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This increase could be attributed, in part, to awareness that has been made through tobacco cessation/reduction marketing strategies that strongly emphasize lung injuries associated with e-cigarette vaping, causing the youth to exploit other options for nicotine consumption [120]

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Gut microbial metabolites reveal diet-dependent metabolic changes induced by nicotine administration

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If you stop taking nicotine for a couple of months, your tolerance gradually reduces, and smaller nicotine dosages can produce the desired buzz once again