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With more than 71 million residents, these states include roughly 22% of the U.S
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Activated mast cells are involved in pathologies of some pulmonary diseases such as COPD, emphysema, asthma, and COVID-19 [27, 157,158,159]
The most plausible threat from bias is that the COVID-19 pandemic resulted in a systematic change to the methods (e.g., to the sampling strategy, response rates or to the data collection methods) affecting particularly the 2020/21 and 2021/22 surveys