For instance, quercetin was shown to increase the abundance of beneficial gut microbes, elevate SCFA levels, suppress inflammatory cytokines, and improve both trabecular architecture and BMD in OVX rat models ( Pueraria lobata (Willd.) Ohwi (Fabaceae), demonstrated anti-osteoporotic effects in OVX rats through microbiota-dependent mechanisms, including improved mucosal barrier integrity, reduced systemic inflammation, and modulation of microbial metabolismparticularly pathways involved in amino acid metabolism, LPS biosynthesis, and butyrate production ( Further evidence from Li et al
STEP 8 Investigators
Matsuda K, Yuasa H, Watnabe J
Side effects were similar to other GLP-based therapies: mild to moderate nausea, transient vomiting, and digestive discomfort during dose escalation
It plays a role in controlling blood sugar managing insulin, and regulating appetite