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The difference in mitochondrial morphology between the two cell lines might therefore indicate different balance between these two processes as rotenone is a well-known inducer of ROS and mitochondrial fragmentation (Frank et al

There were 24 rats per drug (48 total), 12 male and 12 female

[17] [18] This rapid degradation necessitates the development of modified GLP-1 analogues or DPP-4 inhibitors to achieve sustained therapeutic effects

However, we did not detect any of the dienones when methyl was replaced with bulkier substituents, such as isopropyl and tert- butyl groups