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That lowers the entry point

the underlying STEP trials were also Novo Nordisk-sponsored

Here's what to avoid: No COA, or only a generic/undated COA: If a vendor can't provide a lot-specific certificate from an actual third-party lab, assume the product is untested

Other limitations of these trials include the exclusion of sleepy patients with OSA, evaluation of composite rather than individual cardiovascular outcomes, and low PAP adherence [29]

This means orforglipron can be taken in pill form to achieve similar effects, including weight loss and other improvements in metabolic health, like better blood sugar control, lower blood pressure, and reduced cholesterol