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This chapter also investigates various mechanisms of toxicity from the perspectives of pulmonary, inflammation, oxidative stress, DNA damage, apoptosis, transcriptome alterations, and epithelial-mesenchymal transition (EMT), all of which are directly linked to the effects of e-cigs

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[27] It is estimated that each adult smoker consumes 838 [28] cigarettes, equating to about 42 cigarette packs, per year