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But while a federal ban on flavored ENDS seems unlikely while FDA reviews the science and the manufacturers PMTA arguments, these products continue to face the threat of prohibition at the local level, as many state and local authorities and attorneys general[17] push for bans or request FDA to deny PMTAs for flavored ENDS

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When considering all HNCs, approximately 25% constitute HPV positive tumors, with a higher prevalence in oropharyngeal cancer (35.6%, range 11100%) than in the oral cavity (23.5%, range 4080%) or larynx (24%, range 0100%) [9]

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