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Nicorette should be used with caution in cases of: - systemic hypertension cerebrovascular disease - stable angina pectoris - regardless compensated heart failure - vasospasm - peripheral vascular disease ulcer - active duodenal ulcers - excessive thyroid - insulin dependent diabetes (lower insulin doses may be necessary after quitting smoking) - pheochromocytoma (because nicotine provides for the release of catecholamines from the adrenal medulla) - moderate to severe hepatic Only in cases of severe kidney damage, the separation of nicotine metabolites or the related metabolism in jeopardy

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Here we list a few alternatives to cold turkey: Medicine Prescription-only medicines, like Varenicline, Cytisine or Champix, can greatly increase your chances of successfully quitting smoking