glutathione tad SALE! New TAD-600 FDA Approved – NBBGlutathionebyAbby Glutathione RyDocs

Intensive protocols require closer medical monitoring to ensure appropriate tolerance and to assess therapeutic response

In addition to its direct antioxidant functions, glutathione (GSH) contributes to the regeneration of other antioxidants, including vitamins C and E, and is involved in critical processes such as iron homeostasis and mitochondrial integrity

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Indications: Huntington's Chorea (a hyperkinetic movement disorder) A drug of first choice for this condition Side Effects: Sedation Depression (suicidal tendencies) Parkinsonism symptoms Lacks the hypotensive & GI side effects of reserpine due to its selectivity for central VMAT2 Pharmacokinetics: * undergoes rapid hepatic metabolism involving carbonyl reductase and CYP2D6 to 2 active metabolites -dihydrotetrabenazine (-HTBZ) and -dihydrotetrabenazine (-HTBZ), with eventual renal elimination of metabolites the -HTBZ and -HTBZ metabolites are primarily responsible for the pharmacological & therapeutic effects produced by the parent prodrug Readily crosses the blood brain barrier & depletes cerebral monoamine stores

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