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Did it influence her fiction

The oral LD50 of nicotine in dogs is 9.2mg/kg 22

In females with EDS, gynecologic complaints, such as mucosal problems with their genital area [69] , heavy menstrual or intermenstrual bleedings [110] and painful intercourse [71, 111] are commonly encountered with an incidence ranging from 30 to 75%

Though it's nice the smoking awareness campaigns have brought the graphic evils of tobacco to dinner hour TV screens, I have to admit, they're as pointless as the anti-marijuana PSAs of the '60s to the '90s