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Patients considering medically supervised weight loss should be aware of these restrictions: Section 503A pharmacies: Enforcement began April 22, 2025 Section 503B facilities: Must cease by May 22, 2025 Continued compounding may result in FDA enforcement actions Limited exceptions exist for documented allergies or specific medical needs Important Safety Note: The FDA strongly advises against using compounded semaglutide when FDA-approved alternatives are available

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Weeks 5 to 8: building tolerance (0.50 mg per week) The first dose increase

Barriers to coverage Its important to note that Medicare is allowing insurers that provide Part D coverage to establish rules before they cover Wegovy, a practice that might restrict access in the near term and could keep premiums low, said Gretchen Jacobson, vice president of the Medicare program at the Commonwealth Fund