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We previously reported a prospective, multicentr, molecular epidemiology study, the Japan Molecular Epidemiology (JME) study, which included comprehensive smoking information based on a detailed questionnaire and the mutational profiles of 72 genes using next-generation sequencing.14 The prevalence of KRAS , tumour suppressor p53 ( TP53 ) and EGFR mutations in this study were associated with smoking dose
Because there are so many pores, the inner surface area is very large, even in a small filter
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The new index used in the study is more modern than the most widely used dependence survey, the Fagerstrom Test for Nicotine Dependence
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