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This is when the combination typically starts showing clear effects
According to NICE guideline NG28, GLP-1 receptor agonists should be considered when: Triple therapy (metformin and two other oral drugs) is not effective, not tolerated, or contraindicated The patient has a BMI 35 kg/m (or lower in people of Black, Asian and other minority ethnic groups) and specific obesity-related comorbidities The patient has a BMI 40% reduction in non-HDL cholesterol GLP-1 receptor agonist for glycaemic control and weight management (with secondary lipid benefits) Ezetimibe if non-HDL cholesterol reduction is insufficient Lifestyle interventions addressing diet, exercise, and weight Monitoring and follow-up are essential components of cholesterol management
Weight-related examples include exploring the potential for GLP-1s: Reduce the risk of cardiovascular events in adults with obesity and cardiovascular disease (CVD) Reduce complications from heart failure, sleep apnea, peripheral artery disease, and non-alcoholic steatohepatitis (NASH) in patients with obesity Researchers are also evaluating the effects of GLP-1s on diabetic retinopathy and even Alzheimers disease
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It can help brighten affected areas and protect your skin from the harmful effects of the sun
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