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"As a result of this campaign, calls to quit phone lines more than doubled, and visits to the campaigns quit-assistance website more than quadrupled

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What has been lacking until now among individuals with and without psychiatric disorders is a large, randomised controlled trial that directly compares these medications with placebo and an active comparator, and that systematically probes for neuropsychiatric adverse events while smokers are trying to quit. The researchers assessed the relative neuropsychiatric safety and efficacy of varenicline and bupropion compared with nicotine patches and placebo among 8,144 smokers with or without psychiatric illnesses

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