Semaglutide Dosing Schedule and Weight Loss Outcomes Clinical evidence from the STEP trials showed that participants receiving 2.4 mg of semaglutide weekly lost an average of 15% of their body weight over 68 weeks, compared to less than 3% in the placebo group
When unopened and stored properly in the fridge, semaglutide injections approved by the US Food and Drug Administration (FDA) can last in the fridge for quite a whileup until the expiration date printed on the box
In the absence of headtohead comparative trials between tirzepatide and semaglutide in people with obesity or overweight with T2D, this analysis provides indirect evidence that tirzepatide treatment (10 and 15 mg) may have been associated with greater weight and HbA1c reduction than semaglutide (2.4 mg)
The major differences lie in mechanism and efficacy , not in how you administer the medication
This higher strength is important beyond just the scale, as you will see bigger drops in visceral fat, as well as better fasting glucose and blood pressure, more quickly when weight loss is larger and maintained