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demonstrated that RAC1 overexpression notably enhanced ferroptosis in the kidneys of STZ-induced diabetic mice and high glucosetreated podocytes

The beta-3 adrenergic pathway that AOD 9604 activates is highly expressed in visceral adipose tissue, making it a targeted tool for belly fat reduction

As expected by the increased striatal DA, pathways signifying activation of signalling by G-protein-coupled receptors, transmission across chemical synapses and calcium signalling were all positively enriched at 3 months in iSPN + mut (Supplementary Table 1a), whereas genes associated with metabolic pathways such as oxidative phosphorylation (OxPhos) and respiratory electron transport ATP synthesis were significantly downregulated in iSPN + mut compared to iSPN+wt at 3 months (Fig

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