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Supplementary Material A Contributorship Form detailing each authors specific involvement with this content, as well as any supplementary data, are available online at Acknowledgments We thank all of our in-country collaborators for their expertise and assistance with data collection (names of collaborating organizations can be found at We also thank Stephanie Ng, Adami Osho, Kara Robinson, Deana Tremble, Rebecca Lesser, and Mustafa Sakib for coding the tobacco packs for design features and marketing appeals

Conclusion Modern evidence from landmark trials like TRAVERSE 8 and the T-Trials 10 demonstrates that testosterone replacement therapy, when appropriately prescribed and monitored, is both safe and effective for improving quality of life, sexual function, physical function, mood, and metabolic health in men with genuine testosterone deficiency

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