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This is because these substances are active ingredients of high pharmaceutical complexity and high sanitary risk when compounded, particularly in sterile injectable forms, without evidence of stability, sterility, and therapeutic equivalence (Technical Note #200/2025)

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MCF-7 and MCF-7 GPX4 null cells were injected subcutaneously into the mouse flanks, and tumours that reached 150200 mm 3 were randomised to vehicle or palbociclib treatment