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4.2 mtDNA-induced inflammatory responses Akin to bacteria, mtDNA contains hypomethylated CpG motifs that are potent inducers of inflammation (Nakayama and Otsu, 2018)

Twelve pack-years is equal to 10 cigarettes a day for 24 years, 20 cigarettes a day for 12 years or 30 cigarettes a day for eight years

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The erosion of telomeres over time has been linked to aging and disease risks including things like cancer