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Kara Wada, MD, specializing in immunology, explained, GLPs have expanded our understanding of the intersection of metabolic and immune health

Trigonelline, an alkaloid extracted from fenugreek seeds, can reduce hepatic FMO3 activity, inhibit TMA oxidation, and decrease TMAO production, thereby slowing the progression of CKD (Yong et al., 2023) (Figure 9B)

(2021) 37:E4834

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[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Ward M., Hughes C.F., Strain J.J., Reilly R., Cunningham C., Molloy A.M., Horigan G., Casey M., McCarroll K., OKane M., et al