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R.SkobowiatC.ZmijewskiM.et al (2013)

Given that resveratrol has beneficial effects in treating PCOS [16,17] and endometriosis [56] due to its anti-inflammatory properties, which contribute to the regulation of the hypothalamicpituitaryovarian axis [55], it can also promote positive hormonal regulation for new applications such as lipedema treatment through its reported antiestrogenic action in studies of endometriosis, a condition with a hormonal background similar to that of lipedema [56,57,58,59]

It also helps fade dark spots to even out skin tone

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Apremilast is often well-tolerated and possesses a good safety profile relative to conventional systemic treatments