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Comparatively, one study demonstrated that while VPR, Suntag, and SAM systems had multiple orders of magnitude greater transcriptional activation than VP64 alone, there was no more than a single level of magnitude in differences between these three systems [71]

The inflammatory milieu in IBD leads to enhanced ROS generation, causing DNA damage and subsequent 8-OHdG formation (186)

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It is plausible that, had the infant been referred for dental consultation at first presentation (based on the unusual circumstance of a neonatal tooth erupting in the maxilla), an earlier confirmation of diagnosis would have been possible