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These are the same harmful compounds found in traditional tobacco and are major causes of cancer and cellular damage over time. He adds that many patients arriving at clinics suffer from severe coughing, hoarseness, dark or yellow phlegm, and in some cases have been diagnosed with pre-cancerous lesions on the vocal cords

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Mark Stehr, Cigarette tax avoidance and evasion, Journal of Health Economics 24:2 (March 2005): 277-297, [10] Adam J