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PMID 16227005

Women in their 60s and beyond experience thinning of the skin (fragile dermis, age spots, and bruises become more noticeable) with delayed wound healing, along with reduced ability to sense touch, pressure, temperature, etc

Tarantini S, Valcarcel-Ares NM, Yabluchanskiy A, Springo Z, Fulop GA, Ashpole N, et al

Rhbdd3, a member of the rhomboid protease family, negatively regulates DC activation and maintains the balance of Treg and Th17 cells by inhibiting IL-6 production in DCs, thus contributing to the prevention of autoimmune diseases [97]

mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism