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Association of menthol-flavoured cigarette smoking with all-cause and cause-specific mortality risk

To the best of our knowledge, the only study that investigated how nicotine affects TNPs demonstrates that exposure to nicotine ( in vivo ) dramatically down-regulates the expression of TNP1 and TNP2 (Table 2) [96]

Research suggests smoking and tobacco exposure may negatively affect: Sperm count Sperm motility (movement) Sperm morphology (shape) DNA integrity Even when sperm count appears normal, tobacco-related damage may affect fertilization potential

State of California Department of Justice - Office of the Attorney General

Its actually not that different