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Heavy, long-term use increases the risk of cannabis use disorder, more intense withdrawal, and co-occurring mental health concerns, making supervised care safer and more effective

Public Health 10, 25002514 (2013)

The effect of the systematic reduction in flow rate on the gradual build up of the smoulder peak is clearly demonstrated

Smoking, and the consumption of tobacco- or nicotine-based products in general, has developed quite the taboo within contemporary American culture

This step requires more than just mere speculation or conjecture that the speech restriction will advance the interest: [R]ather, a governmental body seeking to sustain a restriction on commercial speech must demonstrate that the harms it recites are real and that its restriction will in fact alleviate them to a material degree (emphasis added)